🌿 SkincareDB

PROPYLPARABEN

INCI Name PROPYLPARABEN
CAS Number 94-13-3
πŸ‡ͺπŸ‡Ί Approved
πŸ‡ΊπŸ‡Έ Approved
πŸ‡―πŸ‡΅ Approved
πŸ‡°πŸ‡· No Data
πŸ‡¬πŸ‡§ Banned

Commonly Found In

🌸FragranceπŸ›‘οΈPreservative

Overview

Propylparaben is a cosmetic preservative in the paraben family, valued for its strong antifungal activity. The EU restricts it to a maximum of 0.14% in leave-on products and prohibits use in products applied to the diaper area for children under 3 (Regulation 358/2014). Studies suggest greater estrogenic potency compared to shorter-chain parabens, which informed the stricter EU limits.

Also known as: propyl p-hydroxybenzoate, propyl 4-hydroxybenzoate, E216, Nipasol M, Tegosept P

Key Benefits

Acts as a preservative; no direct skin-conditioning benefit. Studies suggest stronger antifungal efficacy than methylparaben at the same concentration.

Supporting Research

  • β€’ EU Regulation 358/2014: Restricted propylparaben to 0.14% in leave-on cosmetics and banned in diaper-area products for children under 3 based on endocrine disruption assessment
  • β€’ SCCS/1348/10 (2011): Reviewed endocrine-disruption potential; stricter limits applied relative to shorter-chain parabens

Skin Compatibility Ratings

Comedogenic Rating

0/5

Non-comedogenic at typical use concentrations

Source: CIR Expert Panel

Irritancy Rating

1/5

Low irritancy at cosmetic concentrations; slight sensitization risk in rare cases

Source: CIR Expert Panel

Typical Use Concentration

Range

0.02–0.14% (EU leave-on); up to 0.4% (rinse-off, non-EU)

Optimal

0.05–0.1%

EU Annex V max 0.14% for leave-on; banned in EU diaper-area products for children <3. Japan allows up to 1%. US unrestricted.

Works Well With / Avoid

Works Well With

methylparaben ethylparaben phenoxyethanol

Often combined with methylparaben; EU leave-on concentration limit is 0.14% (as acid); not for use in infant diaper-area products in EU.

Commonly Found In

Moisturizers Shampoos Conditioners Rinse-off Products Body Lotions

Global Regulation Summary

Overview of current status across major international markets.

🚫 1 Banned
βœ… 4 Allowed/Other

Detailed Regional Status

Region Status Max Conc. Conditions Source
πŸ‡ͺπŸ‡Ί EU Allowed - - Official β†—
πŸ‡ΊπŸ‡Έ USA Allowed - - Official β†—
πŸ‡―πŸ‡΅ Japan Allowed - - Official β†—
πŸ‡°πŸ‡· Korea Unknown - - Official β†—
πŸ‡¬πŸ‡§ UK Banned - Follows EU regulations (V/12) Official β†—

🌍 Why Regulations Differ

EU tightened limits on propyl- and butylparaben in 2014 (Regulation 358/2014) due to endocrine disruption concerns, particularly for vulnerable populations (infants). Japan and US have not adopted similar restrictions at typical cosmetic-use concentrations.

Recent Regulatory Changes

  • β€’ EU Regulation 358/2014 (April 2014): Reduced leave-on limit to 0.14% and banned in diaper-area products for children under 3

Regulation Analysis

Regional Agreement

High regulatory divergence

Banned in UK but allowed in EU, USA, Japan.

Category Comparison

There are 219 ingredients in the PERFUMING category. 100% are banned in at least one major market.

Strictness Ranking

1.UKBanned
2.EUAllowed
3.USAAllowed
4.JapanAllowed

🌿 Natural Sources

Occurs naturally in trace amounts in some plants and their metabolites, but commercial propylparaben is exclusively synthetic.

🏭 How It's Made

Produced by esterification of p-hydroxybenzoic acid with propanol (n-propanol) using an acid catalyst. The process yields propyl p-hydroxybenzoate through Fischer esterification.

πŸ’„ Uses in Cosmetics

Used at 0.1-0.4% as a preservative with stronger antifungal activity than methylparaben. EU restricts to max 0.14% (as acid) in leave-on products, banned in diaper area products for children under 3 (Regulation 358/2014, April 2014). Effective against yeasts, molds, and some bacteria.

PERFUMING PRESERVATIVE

πŸ”¬ Other Applications

Used as a food preservative (E216 for propylparaben, E217 for sodium propylparaben) in some countries, though usage is decreasing. Also found in pharmaceuticals.

πŸ’‘ Fun Facts

  • β€’ EU's 2014 restriction followed studies suggesting propylparaben may have weak endocrine-disrupting effects at high concentrations
  • β€’ Propylparaben has a longer alkyl chain than ethylparaben, making it more lipophilic and thus more effective against fungi but also more hormonally active
  • β€’ Japan still allows propylparaben at 1.0% concentration, while the EU has reduced limits to 0.14% for leave-on products

Data Sources

  • β€’ EU Regulation 358/2014 – restriction of propylparaben in cosmetics
  • β€’ SCCS/1348/10 (2011) – SCCS opinion on parabens
  • β€’ CIR Expert Panel – Safety Assessment of Parabens
  • β€’ Japan MHLW cosmetics standards

Last data verification: 2026-04-12

Related Ingredients

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Frequently Asked Questions

What is PROPYLPARABEN used for in cosmetics?

PROPYLPARABEN is primarily used for perfuming in cosmetic products. It also serves as preservative. The ingredient is commonly found in various cosmetic and personal care products.

Which countries regulate PROPYLPARABEN?

PROPYLPARABEN is banned in UK. The ingredient is freely allowed in EU, JP, US.

Are there alternatives to PROPYLPARABEN?

Due to regulatory restrictions on PROPYLPARABEN, cosmetic manufacturers often use alternative ingredients with similar functions. For perfuming, alternatives may include other approved ingredients in the same category. Consult product labels for specific formulations, and look for products compliant with your region's regulations.

Where can I find official regulation information about PROPYLPARABEN?

Official information about PROPYLPARABEN regulations can be found on government websites: EU CosIng database, US FDA Cosmetics page, Japan MHLW cosmetics standards, UK Government cosmetics guidance, and Korea MFDS. Always verify regulatory status with these official sources before making formulation decisions.

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Disclaimer

The information on this website is for educational and informational purposes only and is not intended as medical advice. While we strive for accuracy based on official government databases, cosmetic regulations change frequently. Always consult with a qualified professional or refer to the latest official regulatory documents for compliance. We are not responsible for any actions taken based on the information provided here.