🌿 SkincareDB

ETHYLHEXYL METHOXYCINNAMATE

INCI Name ETHYLHEXYL METHOXYCINNAMATE
CAS Number 5466-77-3
πŸ‡ͺπŸ‡Ί Approved
πŸ‡ΊπŸ‡Έ Approved
πŸ‡―πŸ‡΅ Approved
πŸ‡°πŸ‡· Restricted
πŸ‡¬πŸ‡§ Banned

Commonly Found In

🧴Sunscreen

Overview

ETHYLHEXYL METHOXYCINNAMATE is a cosmetic ingredient primarily used for LIGHT STABILIZER. It is commonly found in various cosmetic formulations and serves important functions in personal care products.

Also known as: Octinoxate, OMC, Parsol MCX, Uvinul MC80, Escalol 557

Key Benefits

Octinoxate is an effective UVB absorber that may help protect skin from sunburn and UV-induced DNA damage. Studies suggest it absorbs UVB radiation (peak ~310 nm) and dissipates it as heat, contributing to SPF values in sunscreen formulations.

Supporting Research

  • β€’ Shaath (1990) – comprehensive review of UV filter mechanisms and octinoxate's UVB absorption profile (Cosmet Toiletries)

Skin Compatibility Ratings

Comedogenic Rating

0/5

Non-comedogenic at typical use concentrations (up to 10%). Widely incorporated in daily-wear SPF products.

Source: CIR Expert Panel; SCCS/1533/14

Irritancy Rating

1/5

Low irritancy in most users; photoallergy documented in photopatch testing studies at rates of approximately 0.5–1%.

Source: SCCS/1533/14; Cardoso et al. 2019 (Contact Dermatitis)

Typical Use Concentration

Range

1–10%

Optimal

5–7.5%

EU Annex VI maximum: 10%. FDA OTC monograph permits up to 7.5%. South Korea permits up to 7.5% for UV protection. Hawaii ban effective January 2021.

Works Well With / Avoid

Works Well With

butyl-methoxydibenzoylmethane benzophenone-3 octocrylene titanium-dioxide

One of the most widely used UVB filters globally. Oil-soluble; incorporated in the oil phase. Provides emollient-like texture. Photo-stable for UVB but does not stabilize avobenzone. Hawaii banned it in 2021 due to coral reef harm concerns.

Commonly Found In

Sunscreens SPF Moisturizers Daily UV Protection Products Lip Balms with SPF

Global Regulation Summary

Overview of current status across major international markets.

🚫 1 Banned
⚠️ 1 Restricted
βœ… 3 Allowed/Other

Detailed Regional Status

Region Status Max Conc. Conditions Source
πŸ‡ͺπŸ‡Ί EU Allowed - - Official β†—
πŸ‡ΊπŸ‡Έ USA Allowed - - Official β†—
πŸ‡―πŸ‡΅ Japan Allowed - - Official β†—
πŸ‡°πŸ‡· Korea Restricted 7.5% When used as UV protection Official β†—
πŸ‡¬πŸ‡§ UK Banned - Follows EU regulations (VI/12) Official β†—

🌍 Why Regulations Differ

Octinoxate is approved across most major markets (EU up to 10%, US up to 7.5%, Japan, Australia). However, it was banned in Hawaii (effective 2021) and faces scrutiny over endocrine activity in animal studies. The FDA classified it as Category III in its 2019 Proposed Rule. Environmental concerns around coral reef toxicity have driven sub-national bans.

Recent Regulatory Changes

  • β€’ Hawaii: Ban effective January 1, 2021 (Act 104, SB 2571)

Regulation Analysis

Regional Agreement

High regulatory divergence

Banned in UK but allowed in EU, USA, Japan.

Category Comparison

There are 34 ingredients in the LIGHT STABILIZER category. 100% are banned in at least one major market.

Strictness Ranking

1.UKBanned
2.KoreaRestricted
3.EUAllowed
4.USAAllowed
5.JapanAllowed

🌿 Natural Sources

Entirely synthetic cinnamate ester derivative. Does not occur naturally but is structurally related to cinnamic acid, which is found in cinnamon and other plants.

🏭 How It's Made

Synthesized by esterifying methoxycinnamic acid with 2-ethylhexanol in the presence of an acid catalyst (typically sulfuric acid) under reflux conditions. Alternative synthesis uses cross metathesis of trans-anethole with 2-ethylhexyl acrylate using nitro-Grela catalyst (86% yield).

πŸ’„ Uses in Cosmetics

Uvb Filter protecting against UVB (280-320 nm) with peak protection at 310 nm. Used at Up to 7.5% in FDA and most global markets; 7.5% maximum in South Korea concentrations. The extended conjugation of the acrylate portion absorbs UVB radiation. Upon absorption, electrons are promoted to higher energy orbitals, then release absorbed energy as heat when returning to ground state. The ethylhexanol portion provides emollient and water-resistant properties.

LIGHT STABILIZER UV ABSORBER UV FILTER

πŸ”¬ Other Applications

Pharmaceutical preparations as UV protectant for drug stability; Hair care products for UV protection of colored hair; Lip balms and lipsticks for UVB protection

πŸ’‘ Fun Facts

  • β€’ Octinoxate was first patented in the 1950s and became widely popular from 1985 onwards.
  • β€’ By the 2000s, octinoxate became the most common active ingredient in sunscreens for UVB protection globally.
  • β€’ Hawaii banned octinoxate effective January 1, 2021 (along with oxybenzone) in the first US state-level sunscreen ingredient ban due to coral reef toxicity concerns.

Related Skin Concerns

Data Sources

  • β€’ EU Cosmetics Regulation Annex VI
  • β€’ FDA OTC Sunscreen Monograph; FDA Proposed Rule 2019
  • β€’ Hawaii Act 104 (2018)
  • β€’ CIR Expert Panel review
  • β€’ Japan MHLW UV filter positive list

Last data verification: 2026-04-16

Related Ingredients

Learn More

Frequently Asked Questions

What is ETHYLHEXYL METHOXYCINNAMATE used for in cosmetics?

ETHYLHEXYL METHOXYCINNAMATE is primarily used for light stabilizer in cosmetic products. It also serves as uv absorber, uv filter. The ingredient is commonly found in various cosmetic and personal care products.

Which countries regulate ETHYLHEXYL METHOXYCINNAMATE?

ETHYLHEXYL METHOXYCINNAMATE is banned in UK. It has concentration limits or usage restrictions in KR. The ingredient is freely allowed in EU, JP, US.

Are there alternatives to ETHYLHEXYL METHOXYCINNAMATE?

Due to regulatory restrictions on ETHYLHEXYL METHOXYCINNAMATE, cosmetic manufacturers often use alternative ingredients with similar functions. For light stabilizer, alternatives may include other approved ingredients in the same category. Consult product labels for specific formulations, and look for products compliant with your region's regulations.

Where can I find official regulation information about ETHYLHEXYL METHOXYCINNAMATE?

Official information about ETHYLHEXYL METHOXYCINNAMATE regulations can be found on government websites: EU CosIng database, US FDA Cosmetics page, Japan MHLW cosmetics standards, UK Government cosmetics guidance, and Korea MFDS. Always verify regulatory status with these official sources before making formulation decisions.

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Disclaimer

The information on this website is for educational and informational purposes only and is not intended as medical advice. While we strive for accuracy based on official government databases, cosmetic regulations change frequently. Always consult with a qualified professional or refer to the latest official regulatory documents for compliance. We are not responsible for any actions taken based on the information provided here.