🌿 SkincareDB

HOMOSALATE

INCI Name HOMOSALATE
CAS Number 118-56-9
πŸ‡ͺπŸ‡Ί Approved
πŸ‡ΊπŸ‡Έ Approved
πŸ‡―πŸ‡΅ Approved
πŸ‡°πŸ‡· No Data
πŸ‡¬πŸ‡§ Banned

Commonly Found In

🧴Sunscreen🌸Fragrance

Overview

HOMOSALATE is a cosmetic ingredient primarily used for FRAGRANCE. It is commonly found in various cosmetic formulations and serves important functions in personal care products.

Also known as: Homosalate, HMS, 3,3,5-Trimethylcyclohexyl salicylate, Helioplex component

Key Benefits

Homosalate is a UVB absorber that may contribute to overall SPF value in combination sunscreen formulations. Studies suggest it provides modest UVB protection (SPF ~4.3 at 10%) and is primarily used to boost the SPF contribution of other UV filters in combination products.

Supporting Research

  • β€’ Shaath (1990) – UVB absorption spectrum and relative efficacy of salicylate UV filters (Cosmet Toiletries)

Skin Compatibility Ratings

Comedogenic Rating

0/5

Non-comedogenic; typically used at concentrations up to 15% in leave-on formulas without occluding pores.

Source: CIR Expert Panel safety assessment

Irritancy Rating

1/5

Generally well-tolerated; low irritancy profile. Mild photoallergy has been documented but is considered rare.

Source: CIR Expert Panel; SCCS/1637/21

Typical Use Concentration

Range

1–15%

Optimal

5–10%

US FDA OTC monograph permits up to 15%. EU: reduced to maximum 7.34% for face products effective July 2025 (SCCS/1618/20). Japan permits use. EU previously allowed 10%.

Works Well With / Avoid

Works Well With

butyl-methoxydibenzoylmethane benzophenone-3 octocrylene ethylhexyl-methoxycinnamate

Weak UVB filter used in combination with other UV filters. Oil-soluble; good vehicle for lipophilic UV filters. FDA data show measurable systemic absorption above 0.5 ng/mL after a single application, prompting Category III designation.

Commonly Found In

Sunscreens SPF Moisturizers Combination UV Filter Products

Global Regulation Summary

Overview of current status across major international markets.

🚫 1 Banned
βœ… 4 Allowed/Other

Detailed Regional Status

Region Status Max Conc. Conditions Source
πŸ‡ͺπŸ‡Ί EU Allowed - - Official β†—
πŸ‡ΊπŸ‡Έ USA Allowed - - Official β†—
πŸ‡―πŸ‡΅ Japan Allowed - - Official β†—
πŸ‡°πŸ‡· Korea Unknown - - Official β†—
πŸ‡¬πŸ‡§ UK Banned - Follows EU regulations (VI/3) Official β†—

🌍 Why Regulations Differ

Homosalate received significant regulatory attention following the SCCS Opinion SCCS/1618/20, which concluded that a concentration of 7.34% is safe but that higher concentrations lack sufficient safety data, particularly regarding endocrine-disrupting potential. The EU reduced its maximum from 10% to 7.34% effective July 2025. The US FDA classifies it as Category III. Japan maintains use at its existing limits.

Recent Regulatory Changes

  • β€’ EU: Maximum concentration reduced from 10% to 7.34% for face products (effective July 2025) per Commission Regulation based on SCCS/1618/20

Regulation Analysis

Regional Agreement

High regulatory divergence

Banned in UK but allowed in EU, USA, Japan.

Category Comparison

There are 122 ingredients in the FRAGRANCE category. 100% are banned in at least one major market.

Strictness Ranking

1.UKBanned
2.EUAllowed
3.USAAllowed
4.JapanAllowed

🌿 Natural Sources

Entirely synthetic salicylate derivative. While salicylic acid occurs naturally in plants, the trimethylcyclohexyl ester form is purely synthetic.

🏭 How It's Made

Synthesized by Fischer-Speier esterification of salicylic acid with 3,3,5-trimethylcyclohexanol (a hydrogenated derivative of isophorone). The reaction uses acid catalysis to form the ester bond between the salicylic acid hydroxyl and the cyclohexanol.

πŸ’„ Uses in Cosmetics

Uvb Filter And Fragrance protecting against 295-315 nm with peak absorption at 306 nm. Used at Up to 15% in US FDA; up to 10% in EU (reduced from higher limits); 7.34% maximum in EU face products effective July 2025 concentrations. The salicylic acid portion absorbs UVB ultraviolet rays (295-315 nm). The hydrophobic trimethylcyclohexyl group provides oil solubility and water resistance. Weak absorber providing only SPF 4.3 at maximum 10% concentration; typically used in combination with other UV filters.

FRAGRANCE UV ABSORBER UV FILTER

πŸ”¬ Other Applications

Fragrance additive in non-sunscreen cosmetics; UV stabilizer in some polymer applications; Component in perfume formulations

πŸ’‘ Fun Facts

  • β€’ Homosalate is one of the most commonly used sunscreen ingredients globally due to its oil solubility and relatively low cost, despite being a weak UV filter on its own.
  • β€’ The European Commission implemented major regulatory changes effective July 1, 2025, reducing the maximum concentration in face products to 7.34% (from 10%) and to only 0.5% in general cosmetic products, based on SCCS safety reviews.
  • β€’ FDA studies show that with even a single application, homosalate can be absorbed through the skin at levels above 0.5 nanograms per milliliter, exceeding the FDA's threshold for mandatory additional safety testing.

Related Skin Concerns

Data Sources

  • β€’ EU SCCS Opinion SCCS/1618/20 on homosalate
  • β€’ EU Cosmetics Regulation Annex VI (amended)
  • β€’ FDA Proposed Rule 2019 (84 FR 6204)
  • β€’ Japan MHLW UV filter positive list
  • β€’ CIR Expert Panel review

Last data verification: 2026-04-16

Related Ingredients

Learn More

Frequently Asked Questions

What is HOMOSALATE used for in cosmetics?

HOMOSALATE is primarily used for fragrance in cosmetic products. It also serves as uv absorber, uv filter. The ingredient is commonly found in perfumes, colognes, and scented cosmetics.

Which countries regulate HOMOSALATE?

HOMOSALATE is banned in UK. The ingredient is freely allowed in EU, JP, US.

Are there alternatives to HOMOSALATE?

Due to regulatory restrictions on HOMOSALATE, cosmetic manufacturers often use alternative ingredients with similar functions. For fragrance, alternatives may include other approved ingredients in the same category. Consult product labels for specific formulations, and look for products compliant with your region's regulations.

Where can I find official regulation information about HOMOSALATE?

Official information about HOMOSALATE regulations can be found on government websites: EU CosIng database, US FDA Cosmetics page, Japan MHLW cosmetics standards, UK Government cosmetics guidance, and Korea MFDS. Always verify regulatory status with these official sources before making formulation decisions.

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Disclaimer

The information on this website is for educational and informational purposes only and is not intended as medical advice. While we strive for accuracy based on official government databases, cosmetic regulations change frequently. Always consult with a qualified professional or refer to the latest official regulatory documents for compliance. We are not responsible for any actions taken based on the information provided here.