🌿 SkincareDB

PHENOL

INCI Name PHENOL
CAS Number 108-95-2
πŸ‡ͺπŸ‡Ί Banned
πŸ‡ΊπŸ‡Έ Approved
πŸ‡―πŸ‡΅ Approved
πŸ‡°πŸ‡· No Data
πŸ‡¬πŸ‡§ Banned

Commonly Found In

πŸͺ₯Oral Care🌸FragranceπŸ›‘οΈPreservative

Overview

Phenol (carbolic acid) is a caustic aromatic compound banned in EU rinse-off cosmetics (Annex II/1175) and restricted at very low concentrations in leave-on products. It is a strong chemical denaturant and antimicrobial that causes severe skin burns at concentrations above approximately 1%. Historically important as the first surgical antiseptic (Lister, 1865), it remains used in medical-grade chemical peels and some oral care products. Its high systemic toxicity via dermal absorption limits any cosmetic application.

Also known as: Phenol, Carbolic Acid, Hydroxybenzene, Phenic Acid, Phenylic Acid

Key Benefits

No skin benefits at cosmetic concentrations. At medical-grade concentrations, phenol chemical peels are used clinically for deep skin resurfacing, but this is a pharmaceutical procedure not a cosmetic application.

Skin Compatibility Ratings

Comedogenic Rating

0/5

Non-comedogenic; not used as a skin conditioning agent.

Source: CIR Expert Panel; ECHA classification

Irritancy Rating

5/5

Severely caustic; concentrations above ~1% cause immediate chemical burns; systemic toxicity (CNS, cardiac, hepatic effects) via rapid dermal absorption; no safe cosmetic-use concentration for rinse-off products

Source: EU Annex II prohibition; toxicological literature

Typical Use Concentration

Range

Not applicable for cosmetics – banned in rinse-off; trace only in leave-on where permitted

Optimal

Not applicable

EU bans phenol in rinse-off cosmetics (Annex II/1175). Medical chemical peel uses 20–88% phenol – a pharmaceutical procedure, not cosmetic.

Works Well With / Avoid

Avoid Combining

all rinse-off cosmetic formulations (banned in EU/UK)

Banned in EU/UK rinse-off cosmetics (Annex II/1175). Very limited permitted use in non-rinse-off products at trace concentrations in some jurisdictions. No legitimate consumer cosmetic application.

Commonly Found In

Oral Care Products (restricted trace use) Antiseptics (historical)

Global Regulation Summary

Overview of current status across major international markets.

🚫 2 Banned
βœ… 3 Allowed/Other

Detailed Regional Status

Region Status Max Conc. Conditions Source
πŸ‡ͺπŸ‡Ί EU Banned - - Official β†—
πŸ‡ΊπŸ‡Έ USA Allowed - - Official β†—
πŸ‡―πŸ‡΅ Japan Allowed - - Official β†—
πŸ‡°πŸ‡· Korea Unknown - - Official β†—
πŸ‡¬πŸ‡§ UK Banned - Follows EU regulations (II/1175) Official β†—

🌍 Why Regulations Differ

The EU banned phenol in rinse-off cosmetics (Annex II/1175) due to its high systemic toxicity potential. Some jurisdictions permit very low concentrations in leave-on products for antiseptic purpose. The US and Japan permit limited cosmetic use but it has largely been replaced by safer alternatives (e.g., cetylpyridinium chloride in oral care).

Regulation Analysis

Regional Agreement

High regulatory divergence

Banned in EU, UK but allowed in USA, Japan.

Category Comparison

There are 84 ingredients in the ANTIMICROBIAL category. 99% are banned in at least one major market.

Strictness Ranking

1.EUBanned
2.UKBanned
3.USAAllowed
4.JapanAllowed

🌿 Natural Sources

Found naturally in coal tar and crude oil. Also present in small amounts in some foods including smoked meats, certain cheeses, and tea. Produced by some plants as a defense mechanism.

🏭 How It's Made

Industrially produced via the cumene process: benzene reacts with propylene to form cumene, which is then oxidized and cleaved to yield phenol and acetone. First isolated from coal tar in 1834.

πŸ’„ Uses in Cosmetics

Used in cosmetic products primarily for antimicrobial, denaturant, deodorant, fragrance, oral care, preservative.

ANTIMICROBIAL DENATURANT DEODORANT FRAGRANCE ORAL CARE PRESERVATIVE

πŸ”¬ Other Applications

Major industrial chemical used in producing plastics (polycarbonate, epoxy resins), pharmaceuticals (aspirin synthesis), disinfectants, and herbicides. Also used in chemical peels at medical-grade concentrations.

πŸ’‘ Fun Facts

  • β€’ Joseph Lister pioneered the use of phenol (then called carbolic acid) as the first surgical antiseptic in 1865, dramatically reducing post-operative infections
  • β€’ Listerine mouthwash was named after Joseph Lister because of his carbolic acid antiseptic work
  • β€’ Bakelite, the world's first fully synthetic plastic (invented 1907), was made from phenol and formaldehyde

Data Sources

  • β€’ EU CosIng database (Annex II/1175)
  • β€’ OECD SIDS – Phenol hazard assessment
  • β€’ FDA 21 CFR cosmetic ingredient status

Last data verification: 2026-04-16

Related Ingredients

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Frequently Asked Questions

Why is PHENOL banned in the EU but allowed in the US?

The EU follows a precautionary principle, banning PHENOL under II/1175 due to potential safety concerns. The US FDA has not found sufficient evidence to prohibit its use, allowing it under different safety assessment standards. This reflects differing regulatory philosophies between the two regions.

Why is PHENOL banned in the EU but allowed in Japan?

The EU prohibits PHENOL (II/1175) based on their strict safety criteria. Japan's Ministry of Health, Labour and Welfare (MHLW) has evaluated the ingredient and permits its use, potentially with different safety data or usage conditions.

What is PHENOL used for in cosmetics?

PHENOL is primarily used for antimicrobial in cosmetic products. It also serves as denaturant, deodorant. The ingredient is commonly found in various cosmetic and personal care products.

Which countries regulate PHENOL?

PHENOL is banned in EU, UK. The ingredient is freely allowed in JP, US.

Are there alternatives to PHENOL?

Due to regulatory restrictions on PHENOL, cosmetic manufacturers often use alternative ingredients with similar functions. For antimicrobial, alternatives may include other approved ingredients in the same category. Consult product labels for specific formulations, and look for products compliant with your region's regulations.

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Disclaimer

The information on this website is for educational and informational purposes only and is not intended as medical advice. While we strive for accuracy based on official government databases, cosmetic regulations change frequently. Always consult with a qualified professional or refer to the latest official regulatory documents for compliance. We are not responsible for any actions taken based on the information provided here.